Parent Gene: GC
Minor Allele: G = 20%
Major Allele: T = 80%
The G allele is associated with:
- Lower Vitamin D levels (R).
- GG – even lower vitamin D levels. [PMID 20418485]
Expression Control
| Increase gene function | Decrease gene function |
Tretinoin (R)Potassium persulfate (R) Non Human Studies: Diclofenac (R)Doxorubicin (R)Genistein (R)N-nitrosomorpholine (R)Silicon Dioxide (R)Thioacetamide (R)Adrenocorticotropin zinc (R)Bleomycin (R) | Acetaminophen (R)Cyclosporine (R)Vehicle Emissions (R)(+)-JQ1 compound (R) Non Human Studies: Diethylnitrosamine (R)Pirinixic acid (R)Dimethylnitrosamine (R)Potassium Dichromate (R)Tacrolimus (R)Bexarotene (R)Bisphenol A (R)Caffeic acid phenethyl ester (R)Chromium nitrate (R)Cobaltous chloride (R)Methylmercury II (R)Nefazodone (R)Nimesulide (R)Ochratoxin A (R)Perfluorododecanoic acid (R)Potassium chromate(VI) (R)Retene (R)Titanium dioxide (R)Clofibrate (R) |